Which of the following best defines 'controlled substances'?

Controlled substances are best defined as drugs that have a high potential for misuse and are monitored by law. This definition encompasses the legal and regulatory framework established to manage substances that can lead to dependence or addiction. Controlled substances are classified into different schedules based on their potential for abuse, accepted medical use, and safety or dependence liability.

Unlike medications available without a prescription, which can include over-the-counter drugs, controlled substances require a prescription because of their potential risks. Herbal supplements and chemotransport medications do not fall under controlled substances as they may not have the same potential for abuse or regulatory oversight. The key aspect of controlled substances is their regulation to prevent misuse and protect public health, making the correct understanding crucial for anyone in the field of prescription and record-keeping.